After departing Viridian City, Route 22 turns south at a line of trees before circling around the bottom of the treeline and passing north through a grassy patch of wild Pokémon. North of the patch, the route turns west, passing over a small hill as well as a small pond. Route 22 then turns south, hopping over a ledge into another patch of grass. Six paces to the south, Route 22 returns west, then north, passing through a hole in the fence outside the checkpoint building. To the northeast, the road goes through a break in a ledge before entering the building, emerging as Route 23 on the north side.